Some
horizontal ridge phenomena include:
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Muehrcke
lines are associated with albumin deficiency (as is kidney disease, and liver
and severe malnutrition), but also seen in chemotherapy. (source
eMedicine). They seem to be a simple interruption of pigmentation.
Beau's
lines are horizontal
lines of darkened cells and linear depressions. They may
be associated with traumas, acute severe illness,
malnutrition, major metabolic condition, chemotherapy or other damaging event,
and is the result of any interruption in the protein formation of the nail plate.
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Mees'
lines or Aldrich-Mees' lines are horizontal lines of discoloration which occur
on the nails of the fingers and toes after an episode of poisoning with
arsenic or thallium or other heavy metals. They can also appear if the subject
is suffering from renal failure. They are typically white bands traversing the
width of the nail. With growth of the nail, they are displaced upward on the nail
and eventually disappear when trimmed. (wikipedea) | | |
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Transverse
Nail Ridges: Horizontal lines
may be a marker of a past episode of severe illness Photo credit,
Josh Fierer, M.D.
(I
wouldn't swear to this - I think this may happen after minor injury?) | | |
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koilonychia
("spoon nails") not exactly a horizontal ridge, this "depression",
but needs to be distinguished. . | | |
Nails
may exhibit many different abnormalities. In
the condition known as koilonychia ("spoon nails"), the nails are
flattened and have concavities. This condition may be associated with iron deficiency
(but it can simply be a normal variant)..
|
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 Leukonychia
striata = white
striations on the nails. (I went to the University
library to look up nail stuff.
They didn't have color copying.) (These
are the sort of white marks people associate with zinc difficiency, aren't they?)
Most
source concur that the white stria are caused by trauma to the nail matrix (the
growth area or "moon"), for instance, wikipedia says, " The most
common cause is injury to the base of the nail (the matrix) where the nail is
formed."
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A
group of oncologists describe how a patient on chemotherapy developed fingernail
anomalies."Two months into his second-line chemotherapy, he developed multiple,
concomitant, transverse and longitudinal black lines in all of his fingernails
and toenails. After an interval of 3 months, he presented a complex pattern of
nail hyperpigmentation, from combined dense horizontal and longitudinal
streaks in some nails to diffuse black discoloration in others (Figure).
Other associated changes included koilonychia, dystrophy, and friability of nail
plates." The point here is that these doctors had no idea why these disfigurations
were occurring. Skinmed.
2007 Mar-Apr;6(2):95-6. "A complex pattern of melanonychia and onycholysis
after treatment with pemetrexed for lung cancer." Dasanu CA, Wiernik PH,
Vaillant J, Alexandrescu DT. | | |
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